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美国Product Overview
Product Name | AM 281 |
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Catalog Number | orb181102 |
Product Properties
Note | For research use only. |
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Formula | C21H19Cl2IN4O2 |
MW | 557.21 |
CAS Number | [202463-68-1] |
SMILES | O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(I)C=C3)=C1C)NN4CCOCC4 |
Product Description
Potent, selective CB1 cannabinoid receptor antagonist/inverse agonist (Ki values are 12 and 4200 nM for CB1 and CB2 receptors respectively). Increases locomotor activity following systemic administration in vivo. Analog of SR141716A (Ki = 14 nM).
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