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Product Overview
| Product Name | AMG517 |
|---|---|
| Catalog Number | orb180918 |
Product Properties
| Note | For research use only. |
|---|---|
| Formula | C20H13F3N4O2S |
| MW | 430.403 |
| CAS Number | [659730-32-2] |
| SMILES | S1C(N([H])C(C([H])([H])[H])=O)=NC2=C(C([H])=C([H])C([H])=C12)OC1C([H])=C(C2C([H])=C([H])C(C(F)(F)F)=C([H])C=2[H])N=C([H])N=1 |
Product Description
AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM.
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