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Product Overview
| Product Name | BMS-833923 (XL-139) |
|---|---|
| Catalog Number | orb180855 |
Product Properties
| Note | For research use only. |
|---|---|
| Formula | C30H27N5O |
| MW | 473.57 |
| CAS Number | [1059734-66-5] |
| SMILES | C(NC1=CC(CNC)=CC=C1C)(=O)C1=CC=C(NC2=NC(C3=CC=CC=C3)=C3C(=N2)C=CC=C3)C=C1 |
Product Description
BMS 833923 is an orally bioavailable inhibitor of Smo. It blocks binding of BODIPY cyclopamine (IC50 = 21 nM) and inhibits Gli activation in cell lines that express wild-type Smo or activated mutant forms of Smo (IC50s = 6-35 nM). BMS 833923 robustly inhi
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