货期
- 咨询
- 现货
- Usually dispatched within 5-10 working days
送货:
美国
Product Overview
| Product Name | HA antibody |
|---|---|
| Catalog Number | orb1463358 |
| Species/Host | Human |
| Reactivity | Virus |
| Conjugation | Unconjugated |
| Immunogen | The original antibody was isolated using phage display from the IgM+ memory B cells of a healthy individual vaccinated against influenza. |
| Target | HA |
| Alternative Names | (click to expand) |
Product Properties
| Concentration | 1 mg/ml |
|---|---|
| Preservatives | PBS with 0.02% Proclin 300. |
| Storage | Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. |
| Note | For research use only. |
| Isotype | IgG |
| Clonality | Monoclonal |
| Purity | Purified |
| Clone ID | CR6261 |
| Uniprot ID | Q9WFX3 |
Product Description
Human monoclonal antibody to HA
Application Notes
| Application Notes | The antibody neutralizes the virus by blocking conformational rearrangements associated with membrane fusion. CR6261 neutralizes multiple influenza subtypes, including H1, H2, H5, H6, H8, and H9, and protects mice from lethal challenge with H1N1 and H5N1 viruses when administered up to five days post-infection (PMID: 19251591). It is reported that Oseltamivir/Zanamivir may congruously improve the therapeutic efficacy of CR6261 (PMID: 22693576). |
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