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Product Overview
Product Name CD163 antibody
Catalog Number orb44713
Species/HostMouse
ReactivityHuman
ConjugationUnconjugated
Tested applicationsFC, IHC-Fr, IP, WB
Immunogen Hairy cell leukemia cells
Target CD163
Alternative Names
Product Properties
Concentration 1 mg/ml
Preservatives Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Store at 2-8°C. Do not freeze.
Note For research use only.
Isotype Mouse IgG1 kappa
ClonalityMonoclonal
Purity Purified by protein-A affinity chromatography.
Clone ID GHI/61
Uniprot ID Q86VB7
Entrez 9332
Product Description

Mouse monoclonal to CD163. CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.

Application Notes
Dilution Range Flow cytometry: Recommended dilution: 1-4 μg/ml.
Application Notes Flow cytometry: Recommended dilution: 1-4 μg/ml.
Validation Images
Flow cytometric analysis of normal human peripheral blood cells using CD163 antibody
Flow cytometric analysis of normal human peripheral blood cells using CD163 antibody
IHC-P of Human spleen tissue using CD163 antibody
IHC-P of Human spleen tissue using CD163 antibody
IHC-P of human placenta tissue using CD163 antibody
IHC-P of human placenta tissue using CD163 antibody
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