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美国Product Overview
Product Name | CD163 antibody |
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Catalog Number | orb44713 |
Species/Host | Mouse |
Reactivity | Human |
Conjugation | Unconjugated |
Tested applications | FC, IHC-Fr, IP, WB |
Immunogen | Hairy cell leukemia cells |
Target | CD163 |
Alternative Names | (click to expand) |
Product Properties
Concentration | 1 mg/ml |
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Preservatives | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Storage | Store at 2-8°C. Do not freeze. |
Note | For research use only. |
Isotype | Mouse IgG1 kappa |
Clonality | Monoclonal |
Purity | Purified by protein-A affinity chromatography. |
Clone ID | GHI/61 |
Uniprot ID | Q86VB7 |
Entrez | 9332 |
Product Description
Mouse monoclonal to CD163. CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.
Application Notes
Dilution Range | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
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Application Notes | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
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