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Product Overview
| Product Name | CD68 Antibody |
|---|---|
| Catalog Number | orb607085 |
| Species/Host | Mouse |
| Reactivity | Human |
| Conjugation | Unconjugated |
| Tested applications | IHC-P |
| Immunogen | A human alveolar macrophage subcellular fraction was used as the immunogen for this anti-CD68 antibody. |
Product Properties
| Preservatives | 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide |
|---|---|
| Storage | Store the anti-CD68 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |
| Note | For research use only. |
| Isotype | Mouse IgG1, kappa |
| Clonality | Monoclonal |
| Purity | Protein G affinity chromatography |
| Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Clone ID | SPM130 |
| Uniprot ID | P34810 |
Product Description
This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
Application Notes
| Dilution Range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
|---|---|
| Application Notes | Optimal dilution of the antibody should be determined by the researcher. |
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