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美国Product Overview
Product Name | CD70 Antibody |
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Catalog Number | orb606159 |
Species/Host | Mouse |
Reactivity | Human |
Conjugation | Unconjugated |
Tested applications | ELISA, FACS, IF, IHC-Fr, Functional Studies |
Immunogen | Recombinant human protein was used as the immunogen for the CD70 antibody. |
Product Properties
Preservatives | 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide |
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Storage | Store the CD70 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |
Note | For research use only. |
Isotype | Mouse IgG1, kappa |
Clonality | Monoclonal |
Purity | Protein G affinity chromatography |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
Clone ID | TNFS7/1026 |
Uniprot ID | P32970 |
Product Description
It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
Application Notes
Dilution Range | ELISA (order BSA/sodium azide-free format for coating),Functional studies (order BSA/sodium azide-free format),Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml for 30 min at RT |
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Application Notes | The concentration stated for each application is a general starting point. Optimal dilution of the CD70 antibody should be determined by the researcher. |
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