货期
- 咨询
- 现货
- Usually dispatched within 5-10 working days
送货:
美国
Product Overview
| Product Name | DS-1205b free base |
|---|---|
| Catalog Number | orb1089355 |
Product Properties
| Note | For research use only. |
|---|---|
| Formula | C41H42FN5O7 |
| MW | 735.8 |
| CAS Number | [1855860-24-0] |
| SMILES | O=C(C1=CN(CC2CCOCC2)C=C(C3=NC=C(C)C=C3)C1=O)NC4=CC=C(C5=CC(C6=CC=C(OC[C@@H]7OCCOC7)C(OC)=C6)=CN=C5N)C(F)=C4 |
Product Description
DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.
Reviews
Write Your Own Review
