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美国Product Overview
Product Name | Elexacaftor |
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Catalog Number | orb1089354 |
Product Properties
Note | For research use only. |
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Formula | C26H34F3N7O4S |
MW | 597.6582 |
CAS Number | [2216712-66-0] |
SMILES | O=C(C1=CC=C(N2N=C(OCC(C)(C)C(F)(F)F)C=C2)N=C1N3C(C)(C)C[C@H](C)C3)NS(=O)(C4=CN(C)N=C4C)=O |
Product Description
Elexacaftor, also known as VX-445 and WHO 11180, is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore Phe508del CFTR protein function in patients with cystic fibrosis when administered with tezacaftor and ivacaftor (VX-445–tezacaftor–ivacaftor).
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