货期
- 咨询
- 现货
- Usually dispatched within 5-10 working days
送货:
美国
Product Overview
| Product Name | IL2R antibody |
|---|---|
| Catalog Number | orb669735 |
| Species/Host | Mouse |
| Reactivity | Human |
| Conjugation | Unconjugated |
| Tested applications | Blocking, ELISA, FC |
| Immunogen | BALB/c mice were immunized with human T lymphoblasts and spleen cells of the immunized animals were fused with X63-Ag8.653 mouse myeloma cells. The supernatants of the resultant hybridomas were screened by a proliferation inhibition assay (inhibition of the human T lymphoblast response to IL-2). Two of those (the clones AHT54 and AHT107) that produced antibodies which inhibited IL-2 dependent proliferation of human T lymphoblasts were selected, cloned and recloned. |
| Target | IL2R |
| Alternative Names | (click to expand) |
Product Properties
| Concentration | 1 mg/ml |
|---|---|
| Preservatives | PBS with 0.02% Proclin 300. |
| Storage | Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. |
| Note | For research use only. |
| Isotype | IgG |
| Clonality | Monoclonal |
| Purity | Purified |
| Clone ID | AHT107 |
| Uniprot ID | P01589 |
Product Description
Mouse monoclonal antibody to IL2R
Application Notes
| Application Notes | This antibody has been used to create a chimeric antibody with a murine variable region and human constant region through the use of recombinant DNA techniques. This gave antigen specificity of the mouse, and immunogenicity, serum half-life, and effector functions of human antibodies. The chimeric antibody has been found to have a greater anti-proliferative effect on T lymphocytes (Rose 1991). AHT107 has been used in ELISAs for the detection of soluble human IL-2R in response to different forms of helminthic and protozoal infections (O. Josimovic et al. 1988). |
|---|
Reviews
Write Your Own Review
