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美国Product Overview
Product Name | KRP-AM1977 |
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Catalog Number | orb1089359 |
Product Properties
Note | For research use only. |
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Formula | C21H24F3N3O4 |
MW | 439.428175926209 |
CAS Number | [848416-07-9] |
SMILES | F[C@@H]1CN(C2=C(C=C3C(C(C(=O)O)=CN(CCF)C3=C2OC)=O)F)C[C@@H]1CNC1CC1 |
Product Description
Lascufloxacin, also known as KRP-AM-1977, is a potent antibacterial drug candidate. Lascufloxacin showed a broad spectrum of activity against various clinical isolates. Especially, lascufloxacin showed the most potent activity against gram-positive bacteria among the quinolones tested. Furthermore, lascufloxacin showed incomplete cross-resistance against existing quinolone-resistant strains. Enzymatic analysis indicated that lascufloxacin showed potent inhibitory activity against both wild-type and mutated target enzymes. Lascufloxacin may be useful in treating infections caused by various pathogens, including quinolone-resistant strains.
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