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美国Product Overview
Product Name | Mavatrep(JNJ-39439335) |
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Catalog Number | orb1089318 |
Product Properties
Note | For research use only. |
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Formula | C25N2OF3H21 |
MW | 422.4423 |
CAS Number | [956274-94-5] |
SMILES | OC(C)(C)C1=CC=CC=C1C2=CC=C3N=C(/C=C/C4=CC=C(C(F)(F)F)C=C4)NC3=C2 |
Product Description
Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6.
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