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美国Product Overview
Product Name | Mouse CD24 Protein |
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Catalog Number | orb651996 |
Reactivity | Mouse |
Conjugation | Unconjugated |
Endotoxins | 1.0 EU per μg |
Target | CD24 |
Alternative Names | (click to expand) |
Product Properties
Form/Appearance | Powder |
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Preservatives | PBS, pH7.4 |
Storage | -20℃ |
Tag | C-10×His |
Note | For research use only. |
Protein Sequence | NP_033976.1 |
Purity | 90% |
MW | 4.6 kDa |
Source | Mouse CD24, His Tag (orb651996) is expressed from human 293 cells (HEK293). It contains AA Asn 27 - Gly 53 (Accession # P24807-1). |
Biological Origin | Mouse |
Expression Region | Asn 27 - Gly 53 |
NCBI | NP_033976.1 |
Product Description
CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Application Notes
Application Notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 4.6 kDa. The protein migrates as 20-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
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