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Product Overview
Product Name Mouse CD24 Protein
Catalog Number orb651996
ReactivityMouse
ConjugationUnconjugated
Endotoxins 1.0 EU per μg
Target CD24
Alternative Names
Product Properties
Form/Appearance Powder
Preservatives PBS, pH7.4
Storage -20℃
Tag C-10×His
Note For research use only.
Protein Sequence NP_033976.1
Purity 90%
MW 4.6 kDa
Source Mouse CD24, His Tag (orb651996) is expressed from human 293 cells (HEK293). It contains AA Asn 27 - Gly 53 (Accession # P24807-1).
Biological Origin Mouse
Expression Region Asn 27 - Gly 53
NCBI NP_033976.1
Product Description

CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.

Application Notes
Application Notes This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 4.6 kDa. The protein migrates as 20-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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