Note	For research use only.
Formula	C₃₁H₃₀CL₂FNO₃
MW	554.47921037674
CAS Number	[2114339-57-8]
SMILES	ClC1C=C(C=CC=1C1CCCC2C=C(C(=O)O)C=CC=2C=1C1C=CC(=CC=1)O[C@H]1CCN(CCCF)C1)Cl

Product Description

SAR439859 is an orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD SAR439859 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells

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