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Product Overview
Product Name VHL ligand 2 hydrochloride
Catalog Number orb611997
Product Properties
Note For research use only.
Formula C21H18F3N5O
MW 413.4
CAS Number [1948273-03-7]
SMILES NC(C(=O)N1CC(O)CC1C(=O)NC(C1C=CC(C2SC=NC=2C)=CC=1)C)C(C)(C)C.Cl
Product Description

VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader.

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