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美国Product Overview
Product Name | VHL ligand 2 hydrochloride |
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Catalog Number | orb611997 |
Product Properties
Note | For research use only. |
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Formula | C21H18F3N5O |
MW | 413.4 |
CAS Number | [1948273-03-7] |
SMILES | NC(C(=O)N1CC(O)CC1C(=O)NC(C1C=CC(C2SC=NC=2C)=CC=1)C)C(C)(C)C.Cl |
Product Description
VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader.
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